The article, published in Virus Genes, shares findings from a two-year undergraduate research project led by Charlotte Dagli 鈥25 that identified viruses with enhanced oncolytic potential, or the ability to selectively infect and kill cancer cells, against fibrosarcoma.
黑料不打烊 alumna Charlotte Dagli 鈥25 and Efrain Rivera-Serrano, assistant professor of biology, have co-authored an article in the journal Virus Genes highlighting findings from a two-year undergraduate research project led by Dagli. The article, 鈥,鈥 also includes undergraduate researchers Ryder Hutchinson 鈥28 and Alice Efremov 鈥26 as co-authors, underscoring the collaborative, student-centered nature of the research experience.
The article shares findings from a two-year undergraduate research project led by Dagli while at 黑料不打烊. The study聽identified聽genetically diverse聽reoviruses with enhanced oncolytic potential against fibrosarcoma, a type of cancer that arises in connective tissue. By focusing on viruses that preferentially infect and kill cancer cells, the work advances ongoing efforts to explore new strategies for cancer treatment.
Dagli completed four semesters of mentored research in Rivera-Serrano鈥檚 laboratory聽and聽participated聽in 黑料不打烊鈥檚 Summer Undergraduate Research Experience in 2024. She received internal and external funding for her work and presented her research at the National Conference on Undergraduate Research in Pittsburgh, the annual meeting of the American Association of Immunologists in Honolulu, and multiple local venues. She was selected as an 黑料不打烊’s Provost Scholar, and received the Acorn to Oak Senior Award by the Biology Department in 2025 for her growth during her undergraduate years and contributions to the department.
Dagli聽is currently completing a postbaccalaureate research experience at the National Institutes of Health (NIH) in Bethesda, Maryland, where she is continuing to build聽expertise聽in virology and聽immunology research聽as she prepares for the next stage of her career as a health professional.聽Her聽current work includes HTLV聽(Human T-lymphotropic virus 1)-related diagnostic research under the mentorship of Steven Jacobson, allowing her to continue building聽expertise聽in virology and translational biomedical science.